研究领域（方向） 1.脑神经疾病的分子机制 2.法医学 3.成瘾药物体内代谢分析与中药戒毒 4.药物人体内痕量检测分析技术 个人及工作简历 1982.9-1987.7 西安医科大学 医疗专业 学士 1990.9-1993.7 西安医科大学 法医学 硕士 1999.9-2003.11 西安交通大学 法医学 博士 1987.7至今 西安交通大学医学部法医学院任教 2005.5-2006.8 美国，美国加州大学，访问学者 科研项目 1.用D1敲除小鼠模型研究fos转录因子在MA依赖中的调控作用（教育部留学回国启动基金 08回国基金01） 2.Fos 转录因子泛素化在甲基安非他命依赖中的调控作用（陕西省自然科学基金SJ08C226） 3．△FosB 稳定性机制在甲基苯丙胺慢性成瘾中的调控作用（国家自然科学基金30973366） 4.ΔFosB 及其上游信号转导通路的调控机制及其人工干预对MA 慢性依赖小鼠行为学变化的影响（国家自然科学基金81273351） 5.MA成瘾相关通路中ΔFosB作用机制的研究 （陕西省科学技术研究发展计划项目2012kw-36-02） 6.基于microRNAs与Glu-NMDAR神经递质系统在甲基苯丙胺依赖中的分子机制研究（国家自然科学基金81471818） 7.伏隔核多巴胺D3受体与NMDA受体相互作用参与吗啡行为敏化的分子机制（国家自然科学基金81373253） 8. miR-486-3p在甲基苯丙胺诱导精神障碍中的分子作用机制研究（国家自然科学基金81871530） 学术及科研成果、专利、论文 论文： (1) Qiao, Chuchu; Qian, Hongyan; Wang, Jue; Zhao, Tingting; Ma, Pengyu; Wang, Sicen; Zhang, Tao; Liu, Xinshe; PD173074 blocks G1/S transition via CUL3-mediated ubiquitin protease in HepG2 and Hep3B cells. , PLos One, 2020, 15(6): e0234708. (期刊论文) (2) Qian, Hongyan; Wang, Jing; Shang, Qing; Xiao, Jing; Chen, Gang; Gao, Baoyao; Liang, Min; Li, Tao*; Liu, Xinshe*; The effect of protein phosphatase 2A inhibitor LB100 on regulating methamphetamine induced conditioned place preference in mice. , Neuroscience Letters, 2020, 721: 134817. (期刊论文) (3) Chen, Gang; Li, Tao*; Xiao, Jing; Wang, Jing; Shang, Qing; Qian, Hongyan; Qiao, Chuchu; Zhang, Ping; Chen, Teng; Liu, Xinshe*; Ifenprodil Attenuates Methamphetamine-Induced Behavioral Sensitization Through the GluN2B-PP2A-AKT Cascade in the Dorsal Striatum of Mice. , Neurochemical Research, 2020, 45(4): 891-901. (期刊论文) (6) Xiong, Jing; Zheng, Tian jiao; Shi, Yan*; Wei, Feng; Ma, Shuang cheng; He, Lan; Wang, Si cen; Liu, Xin she*; Analysis of the fingerprint profile of bioactive constituents of traditional Chinese medicinal materials derived from animal bile using the HPLC-ELSD and chemometric methods: An application of a reference scaleplate , Journal of Pharmaceutical and Biomedical Analysis, 2019, 174: 50-56. (期刊论文) (8) Jia, Xiaodi; Zhang, Tianxiao; Li, Lu; Fu, Dongke; Lin, Huali; Chen, Gang; Liu, Xinshe; Guan, Fanglin; Two-Stage Additional Evidence Support Association of Common Variants in the HDAC3 With the Increasing Risk of Schizophrenia Susceptibility , American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 2016, 171(8): 1105-1111. (期刊论文) (9) Li, Chunlei; Wei, Fen; Muhammad, Saqib; Yang, Guangde; Wang, Sicen; Liu, Xinshe; A cost-effective LC-MS/MS method for identification and quantification of a-amanitin in rat plasma: Application to toxicokinetic study , Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2017, 1064: 36-39. (期刊论文) (10) Guan, Fanglin; Lin, Huali; Chen, Gang; Li, Lu; Chen, Teng; Liu, Xinshe; Han, Jiuqiang; Li, Tao; Evaluation of association of common variants in HTR1A and HTR5A with schizophrenia and executive function , Scientific Reports, 2016, 6: 38048. (期刊论文) (11) Guan, Fanglin; Wei, Shuguang; Zhang, Chen; Zhang, Hongbo; Zhang, Bao; Xing, Bo; Feng, Zufei; Gao, Chengge; Liu, Xinshe*; Li, Shengbin; A population-based association study of 2q32.3 and 8q21.3 loci with schizophrenia in Han Chinese , Journal of Psychiatric Research, 2013, 47(6): 712-717. (期刊论文) (12) Li, Lu; Qiao, Chuchu; Chen, Gang; Qian, Hongyan; Hou, Ying; Li, Tao*; Liu, Xinshe*; ifenprodil attenuates the acquisition and expression of methamphetamine-induced behavioral sensitization and activation of ras-erk12 cascade in the caudate putamen, Neuroscience, 2016, 335: 20-29. (期刊论文) (13) Li, Lu; Liu, Xinshe*; Qiao, Chuchu; Chen, Gang; Li, Tao*; Ifenprodil Attenuates Methamphetamine-Induced Behavioral Sensitization and Activation of Ras-ERK-Delta FosB Pathway in the Caudate Putamen , Neurochemical Research, 2016, 41(10): 2636-2644. (期刊论文) (14) Lin, Dan; Qiao, Li-man; Zhang, Yu-niao; Liu, Yuan; Liu, Xin-she*; Simultaneous determination of nintedanib and its metabolite by UPLC-MS/MS in rat plasma and its application to a pharmacokinetic study , Journal of Pharmaceutical and Biomedical Analysis, 2016, 117: 173-177. (期刊论文) (15) Guan, Fanglin; Zhang, Tianxiao; Liu, Xinshe; Han, Wei; Lin, Huali; Li, Lu; Chen, Gang; Li, Tao; Evaluation of voltage-dependent calcium channel gamma gene families identified several novel potential susceptible genes to schizophrenia. , Scientific Reports, 2016, 6: 24914-24914. (期刊论文) (16) Lin, Dan; Wang, Zhe; Li, Junwei; Wang, Li; Wang, Shuanghu; Hu, Guo-Xin; Liu, Xinshe*; The Effect of Apatinib on the Metabolism of Carvedilol Both in vitro and in vivo , Pharmacology, 2016, 97(1-2): 31-37. (期刊论文) (17) Guan, Fanglin; Li, Lu; Qiao, Chuchu; Chen, Gang; Yan, Tinglin; Li, Tao; Zhang, Tianxiao; Liu, Xinshe; Evaluation of genetic susceptibility of common variants in CACNA1D with schizophrenia in Han Chinese. , Scientific Reports, 2015, 5: 12935-12935. (期刊论文) 成果奖：毒品成瘾的关键分子机制及干预策略研究 省部二等奖 陕西省人民政府 第三 2016.9